I even think a cheap once a week shot might do that! The direction and magnitude of improved health with GLP-1s is impressive. As with all drugs used over a large population there will be some people who will have side effects - even severe ones. We have to consider the counterfactual. Many with obesity will die prematurely (much as many with risk factors for cardiovascular disease will die prematurely).
... And multiple studies and met-analyses have demonstrated the clinical effectiveness of the polypill approach to CV and stroke outcomes.
https://pubmed.ncbi.nlm.nih.gov/37385176/
Wait until a cheap oral GLP1 arrives in the market and then everyone will be on the polypill!
I even think a cheap once a week shot might do that! The direction and magnitude of improved health with GLP-1s is impressive. As with all drugs used over a large population there will be some people who will have side effects - even severe ones. We have to consider the counterfactual. Many with obesity will die prematurely (much as many with risk factors for cardiovascular disease will die prematurely).